Brief Information of the Compound and Protein
Compound Name
N-[3-[[5-cyclopropyl-2-[[3-methyl-1-(2,2,2-trifluoroethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]amino]propyl]cyclobutanecarboxamide
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PubChem ID
CID: 145900916
Canonical SMILES
Cc1nn(CC(F)(F)F)cc1Nc1ncc(C2CC2)c(NCCCNC(=O)C2CCC2)n1
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Compound Formula C21H28F3N7O
Compound Structure
Protein Name
Serine/threonine-protein kinase TBK1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
Other protein kinase group
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Other protein kinase IKK family
Uniprot ID
Q9UHD2
Gene Name
TBK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 2680 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 192 nM