Brief Information of the Compound and Protein
Compound Name
[(3S)-3-(3,5-difluorophenyl)-3,4-dihydropyrazol-2-yl]-[3-(2-fluorophenoxy)azetidin-1-yl]methanone
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Canonical SMILES
Fc1cc(F)cc(c1)[C@@H]1CC=NN1C(=O)N1CC(C1)Oc1ccccc1F
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Compound Formula C19H16F3N3O2
Compound Structure
Protein Name
Receptor-interacting serine/threonine-protein kinase 1
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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TKL protein kinase group
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TKL protein kinase RIPK family
Uniprot ID
Q13546
Gene Name
RIPK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
EC50 = 3.1 nM
   TI
   LI
   LO
   TS