Brief Information of the Compound and Protein
Compound Name
 Compound Info 
5-[(2S,6R)-2-[[6-(3-amino-3-methylazetidin-1-yl)spiro[1H-furo[3,4-c]pyridine-3,3'-azetidine]-1'-yl]methyl]-6-methylmorpholin-4-yl]-2-deuterioquinoline-8-carbonitrile
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 PubChem ID
CID: 156388264
Canonical SMILES
[2H]c1ccc2c(ccc(C#N)c2n1)N1C[C@@H](C)O[C@@H](CN2CC3(C2)OCc2cc(ncc32)N2CC(C)(N)C2)C1
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Compound Formula C29H33N7O2
Compound Structure
Protein Name
 Protein Info 
Toll-like receptor 9
Protein Classification
Membrane receptor
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Toll-like and Il-1 receptors
Uniprot ID
Q9NR96
Gene Name
TLR9
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000685 HEK-Blue hTLR9
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 40 nM
   TI
   LI
   LO
   TS