Brief Information of the Compound and Protein
Compound Name
4-[(2R,6S)-2-methyl-6-[[6-(6-methyl-2,6-diazaspiro[3.3]heptan-2-yl)spiro[1H-2-benzofuran-3,3'-azetidine]-1'-yl]methyl]morpholin-4-yl]pyrazolo[1,5-a]pyridine-7-carbonitrile
    Show/Hide
PubChem ID
CID: 164578694
Canonical SMILES
C[C@@H]1CN(C[C@H](CN2CC3(C2)OCc2cc(ccc32)N2CC3(CN(C)C3)C2)O1)c1ccc(C#N)n2nccc12
    Show/Hide
Compound Formula C30H35N7O2
Compound Structure
Protein Name
Toll-like receptor 8
Protein Classification
Membrane receptor
>
Toll-like and Il-1 receptors
Uniprot ID
Q9NR97
Gene Name
TLR8
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000381 HEK-Blue hTLR8 Homo sapiens (Human)  1
1
IC50 = 40 nM
   TI
   LI
   LO
   TS