Brief Information of the Compound and Protein
Compound Name
6-(4-cyclopentylpiperazin-1-yl)-N-[(4-fluorophenyl)methyl]-9-(3-pyrrolidin-1-ylpropyl)purin-2-amine
    Show/Hide
PubChem ID
CID: 151935817
Canonical SMILES
Fc1ccc(CNc2nc(N3CCN(CC3)C3CCCC3)c3ncn(CCCN4CCCC4)c3n2)cc1
    Show/Hide
Compound Formula C28H39FN8
Compound Structure
Protein Name
Toll-like receptor 9
Protein Classification
Membrane receptor
>
Toll-like and Il-1 receptors
Uniprot ID
Q9NR96
Gene Name
TLR9
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000686 HEK-Blue hTLR7 Homo sapiens (Human)  1
1
IC50 = 100 nM
   TI
   LI
   LO
   TS