Brief Information of the Compound and Protein
Compound Name
 Compound Info 
US9227956, 16
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 PubChem ID
CID: 86271238
Canonical SMILES
Clc1cccnc1N([C@@H]1CCCNC1)C(=O)c1ccc(cc1)-n1nnc2cccnc12
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Compound Formula C22H20ClN7O
Compound Structure
Protein Name
 Protein Info 
Proprotein convertase subtilisin/kexin type 9
Protein Classification
Enzyme
>
Protease
>
Serine protease
>
Serine protease SB clan
>
Serine protease S8A subfamily
Uniprot ID
Q8NBP7
Gene Name
PCSK9
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000040 THP-1
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 750 nM
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