Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-(3-chloropyridin-2-yl)-4-[6-(methylamino)pyrazin-2-yl]-N-[(3R)-piperidin-3-yl]benzamide
    Show/Hide
 PubChem ID
CID: 145960817
Canonical SMILES
CNc1cncc(n1)-c1ccc(cc1)C(=O)N([C@@H]1CCCNC1)c1ncccc1Cl
    Show/Hide
Compound Formula C22H23ClN6O
Compound Structure
Protein Name
 Protein Info 
Proprotein convertase subtilisin/kexin type 9
Protein Classification
Enzyme
>
Protease
>
Serine protease
>
Serine protease SB clan
>
Serine protease S8A subfamily
Uniprot ID
Q8NBP7
Gene Name
PCSK9
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000040 THP-1
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 3100 nM
   TI
   LI
   LO
   TS