Brief Information of the Compound and Protein
Compound Name
(E)-3-(3,5-Difluoro-4-((5R)-4-(2-fluoro-2-methylpropyl)-1,2,3,3a,4,5,6,10c-octahydrocyclopenta[5,6]pyrido[3,4-b]indol-5-yl)phenyl)acrylic Acid
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PubChem ID
CID: 166629053
Canonical SMILES
CC(C)(F)CN1C2CCCC2c2c([nH]c3ccccc23)[C@H]1c1c(F)cc(/C=C/C(=O)O)cc1F
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Compound Formula C27H27F3N2O2
Compound Structure
Protein Name
Estrogen receptor
Protein Classification
Transcription factor
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Nuclear receptor
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Nuclear hormone receptor subfamily 3
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Nuclear hormone receptor subfamily 3 group A
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Nuclear hormone receptor subfamily 3 group A member 1
Uniprot ID
P03372
Gene Name
ESR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000083 MCF-7 Homo sapiens (Human)  1
1
EC50 = 0.35 nM
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