Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(5R)-4-(5-bromothiophene-2-carbonyl)-5-(3,5-dimethylphenyl)-7-methyl-3,5-dihydro-1H-1,4-benzodiazepin-2-one
    Show/Hide
 PubChem ID
CID: 146026048
Canonical SMILES
Cc1ccc2NC(=O)CN([C@H](c3cc(C)cc(C)c3)c2c1)C(=O)c1ccc(Br)s1
    Show/Hide
Compound Formula C23H21BrN2O2S
Compound Structure
Protein Name
 Protein Info 
Protein arginine N-methyltransferase 6
Protein Classification
Epigenetic regulator
>
Writer
>
Protein methyltransferase
>
Protein arginine methyltransferase
Uniprot ID
Q96LA8
Gene Name
PRMT6
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000025 HEK-293T
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 600 nM
   TI
   LI
   LO
   TS
2
IC50 = 900 nM
   TI
   LI
   LO
   TS
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 77 nM
   TI
   LI
   LO
   TS