Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[3-[(2S,5R)-6-amino-5-ethylsulfonyl-2-(fluoromethyl)-5-methyl-3,4-dihydropyridin-2-yl]-4-fluorophenyl]-2,2-difluoro-[1,3]dioxolo[4,5-c]pyridine-6-carboxamide
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Canonical SMILES
CCS(=O)(=O)[C@]1(C)CC[C@](CF)(N=C1N)c1cc(NC(=O)c2cc3OC(F)(F)Oc3cn2)ccc1F
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Compound Formula C22H22F4N4O5S
Compound Structure
Protein Name
 Protein Info 
Beta-secretase 2
Protein Classification
Enzyme
>
Hydrolase
Uniprot ID
Q9JL18
Gene Name
BACE2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000613 MIN6
 Cell Line Info 
Mus musculus (Mouse)  1
1
IC50 = 309 nM
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