Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[3-[(2S,5R)-6-amino-2-(fluoromethyl)-5-methyl-5-propan-2-ylsulfonyl-3,4-dihydropyridin-2-yl]-4-fluorophenyl]-2,2-difluoro-[1,3]dioxolo[4,5-c]pyridine-6-carboxamide
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 PubChem ID
CID: 166634659
Canonical SMILES
CC(C)S(=O)(=O)[C@]1(C)CC[C@](CF)(N=C1N)c1cc(NC(=O)c2cc3OC(F)(F)Oc3cn2)ccc1F
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Compound Formula C23H24F4N4O5S
Compound Structure
Protein Name
 Protein Info 
Beta-secretase 1
Protein Classification
Enzyme
>
Protease
>
Aspartic protease
>
Aspartic protease AA clan
>
Aspartic protease A1A subfamily
Uniprot ID
P56817
Gene Name
BACE1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000151 SK-N-BE(2)
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 6.8 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 10 nM