Brief Information of the Compound and Protein
Compound Name
1-[4-[7-(dimethylamino)quinazolin-4-yl]oxyphenyl]-3-[1-(1,3-thiazol-2-yl)ethyl]urea
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Canonical SMILES
CC(NC(=O)Nc1ccc(Oc2ncnc3cc(ccc23)N(C)C)cc1)c1nccs1
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Compound Formula C22H22N6O2S
Compound Structure
Protein Name
Macrophage colony-stimulating factor 1 receptor
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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TK protein kinase group
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Tyrosine protein kinase PDGFR family
Uniprot ID
P07333
Gene Name
CSF1R
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 1.41 nM
   TI
   LI
   LO
   TS