Brief Information of the Compound and Protein
Compound Name
N-[2-(2,5-difluorophenyl)pyridin-4-yl]-2-(4-methylsulfonylphenyl)pyridin-4-amine
    Show/Hide
Canonical SMILES
CS(=O)(=O)c1ccc(cc1)-c1cc(Nc2ccnc(c2)-c2cc(F)ccc2F)ccn1
    Show/Hide
Compound Formula C23H17F2N3O2S
Compound Structure
Protein Name
TGF-beta receptor type-1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase STKR family
>
TKL protein kinase STKR Type 1 subfamily
Uniprot ID
P36897
Gene Name
TGFBR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 225.9 nM
   TI
   LI
   LO
   TS