Brief Information of the Compound and Protein
Compound Name
2-[4-[4-[2-(2,5-difluorophenyl)pyrrolo[2,3-d]pyrimidin-7-yl]quinolin-7-yl]pyrazol-1-yl]-N,N-dimethylethanamine
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Canonical SMILES
CN(C)CCn1cc(cn1)-c1ccc2c(ccnc2c1)-n1ccc2cnc(nc12)-c1cc(F)ccc1F
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Compound Formula C28H23F2N7
Compound Structure
Protein Name
TGF-beta receptor type-1
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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TKL protein kinase group
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TKL protein kinase STKR family
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TKL protein kinase STKR Type 1 subfamily
Uniprot ID
P36897
Gene Name
TGFBR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 91.72 nM
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