Brief Information of the Compound and Protein
Compound Name
7-[1-[2-(dimethylamino)ethyl]pyrazol-4-yl]-N-[2-(2-fluorophenyl)pyridin-4-yl]quinolin-4-amine
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Canonical SMILES
CN(C)CCn1cc(cn1)-c1ccc2c(Nc3ccnc(c3)-c3ccccc3F)ccnc2c1
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Compound Formula C27H25FN6
Compound Structure
Protein Name
TGF-beta receptor type-1
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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TKL protein kinase group
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TKL protein kinase STKR family
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TKL protein kinase STKR Type 1 subfamily
Uniprot ID
P36897
Gene Name
TGFBR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 0.82 nM
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