Brief Information of the Compound and Protein
Compound Name
N-[2-(2,5-difluorophenyl)pyridin-4-yl]-7-thiophen-3-ylquinolin-4-amine
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Canonical SMILES
Fc1ccc(F)c(c1)-c1cc(Nc2ccnc3cc(ccc23)-c2ccsc2)ccn1
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Compound Formula C24H15F2N3S
Compound Structure
Protein Name
TGF-beta receptor type-1
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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TKL protein kinase group
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TKL protein kinase STKR family
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TKL protein kinase STKR Type 1 subfamily
Uniprot ID
P36897
Gene Name
TGFBR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 10.95 nM
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