Brief Information of the Compound and Protein
Compound Name
4-[6-(2,5-difluorophenyl)imidazo[1,2-a]pyridin-3-yl]-7-(4-methylsulfonylphenyl)quinoline
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Canonical SMILES
CS(=O)(=O)c1ccc(cc1)-c1ccc2c(ccnc2c1)-c1cnc2ccc(cn12)-c1cc(F)ccc1F
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Compound Formula C29H19F2N3O2S
Compound Structure
Protein Name
TGF-beta receptor type-1
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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TKL protein kinase group
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TKL protein kinase STKR family
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TKL protein kinase STKR Type 1 subfamily
Uniprot ID
P36897
Gene Name
TGFBR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 2744 nM
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