Brief Information of the Compound and Protein
Compound Name
(R)-6-chloro-N-(1-cyclobutylpyrrolidin-3-yl)-3-(1-(trifluoromethyl)-1H-pyrazol-4-yl)-1H-indazol-5-amine
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Canonical SMILES
FC(F)(F)n1cc(-c2n[nH]c3cc(Cl)c(N[C@@H]4CCN(C5COC5)C4)cc23)cn1
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Compound Formula C18H18ClF3N6O
Compound Structure
Protein Name
Tyrosine-protein kinase receptor UFO
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Axl family
Uniprot ID
P30530
Gene Name
AXL
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 26300 nM
   TI
   LI
   LO
   TS