Brief Information of the Compound and Protein
Compound Name
(R)-2-(4-(6-chloro-5-(pyrrolidin-3-ylamino)-1H-indazol-3-yl)-1H-pyrazol-1-yl)benzonitrile
    Show/Hide
Canonical SMILES
N#Cc1ccccc1-n1cc(-c2n[nH]c3cc(Cl)c(N[C@@H]4CCNC4)cc23)cn1
    Show/Hide
Compound Formula C21H18ClN7
Compound Structure
Protein Name
Tyrosine-protein kinase receptor UFO
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Axl family
Uniprot ID
P30530
Gene Name
AXL
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 3540 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 3200 nM