Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-butyl-5-[(3S)-3-(5-chloropyridin-2-yl)pyrrolidine-1-carbonyl]-3-(2,6-dimethoxyphenyl)-6-hydroxypyrimidin-4-one
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Canonical SMILES
CCCCc1nc(=O)c(C(=O)N2CC[C@@H](C2)c2ccc(Cl)cn2)c(O)n1-c1c(OC)cccc1OC
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Compound Formula C26H29ClN4O5
Compound Structure
Protein Name
 Protein Info 
Apelin receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Neuropeptide receptor
Uniprot ID
Q9JHG3
Gene Name
APLNR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000025 HEK-293T
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 0.063 nM
   TI
   LI
   LO
   TS