Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-(3-fluoro-2-hydroxyphenyl)-6-methyl-3-(2-phenylethyl)-5-(5-pyridin-2-ylthiophen-2-yl)pyrimidin-4-one
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 PubChem ID
CID: 135956388
SID: 92298753
Canonical SMILES
Cc1nc(-c2cccc(F)c2O)n(CCc2ccccc2)c(=O)c1-c1ccc(s1)-c1ccccn1
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Compound Formula C28H22FN3O2S
Compound Structure
Protein Name
 Protein Info 
Extracellular calcium-sensing receptor
Protein Classification
Membrane receptor
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Family C G protein-coupled receptor
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Ion receptor (family C GPCR)
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Calcium sensing receptor
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Calcium sensing receptor
Uniprot ID
P41180
Gene Name
CASR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 50 nM
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