Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1'-[6-cyano-5-(trifluoromethyl)pyridin-3-yl]-6-fluoro-N-methyl-3'-(2-methylpropyl)-5'-oxo-2'-sulfanylidenespiro[1,3-dihydroindene-2,4'-imidazolidine]-5-carboxamide
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Canonical SMILES
CNC(=O)c1cc2CC3(Cc2cc1F)N(CC(C)C)C(=S)N(C3=O)c1cnc(C#N)c(c1)C(F)(F)F
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Compound Formula C24H21F4N5O2S
Compound Structure
Protein Name
 Protein Info 
Androgen receptor
Protein Classification
Transcription factor
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Nuclear receptor
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Nuclear hormone receptor subfamily 3
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Nuclear hormone receptor subfamily 3 group C
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Nuclear hormone receptor subfamily 3 group C member 4
Uniprot ID
P10275
Gene Name
AR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000141 LNCaP
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 102 nM
   TI
   LI
   LO
   TS