Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-deuterio-5-[(2S,6R)-11-(2,6-diazaspiro[3.4]octan-6-yl)-6-methyl-4,7,10-triazatricyclo[7.4.0.02,7]trideca-1(9),10,12-trien-4-yl]quinoline-8-carbonitrile
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 PubChem ID
CID: 156388115
Canonical SMILES
[2H]c1ccc2c(ccc(C#N)c2n1)N1C[C@H]2N(Cc3nc(ccc23)N2CCC3(CNC3)C2)[C@H](C)C1
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Compound Formula C27H29N7
Compound Structure
Protein Name
 Protein Info 
Toll-like receptor 8
Protein Classification
Membrane receptor
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Toll-like and Il-1 receptors
Uniprot ID
Q9NR97
Gene Name
TLR8
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000381 HEK-Blue hTLR8
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 0.7 nM
   TI
   LI
   LO
   TS