Brief Information of the Compound and Protein
Compound Name
2-deuterio-5-[(2S,6R)-6-methyl-11-piperidin-4-yloxy-4,7,10-triazatricyclo[7.4.0.02,7]trideca-1(9),10,12-trien-4-yl]quinoline-8-carbonitrile
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PubChem ID
CID: 156388124
Canonical SMILES
[2H]c1ccc2c(ccc(C#N)c2n1)N1C[C@H]2N(Cc3nc(OC4CCNCC4)ccc23)[C@H](C)C1
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Compound Formula C26H28N6O
Compound Structure
Protein Name
Toll-like receptor 8
Protein Classification
Membrane receptor
>
Toll-like and Il-1 receptors
Uniprot ID
Q9NR97
Gene Name
TLR8
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000381 HEK-Blue hTLR8 Homo sapiens (Human)  1
1
IC50 < 0.3 nM
   TI
   LI
   LO
   TS