Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-[4-[3-(cyclobutyloxymethyl)piperidin-1-yl]piperidin-1-yl]-N-[(3,5-difluoropyridin-2-yl)methyl]-1,3-thiazole-5-carboxamide
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Canonical SMILES
Fc1cnc(CNC(=O)c2cnc(s2)N2CCC(CC2)N2CCCC(COC3CCC3)C2)c(F)c1
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Compound Formula C25H33F2N5O2S
Compound Structure
Protein Name
 Protein Info 
Alpha-2C adrenergic receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Adrenergic receptor
Uniprot ID
P18825
Gene Name
ADRA2C
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 0.085 nM
   TI
   LI
   LO
   TS