Brief Information of the Compound and Protein
Compound Name
3-[[[4-cyclohexyl-6-(trifluoromethyl)pyrimidin-2-yl]amino]methyl]phenol
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Canonical SMILES
Oc1cccc(CNc2nc(cc(n2)C(F)(F)F)C2CCCCC2)c1
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Compound Formula C18H20F3N3O
Compound Structure
Protein Name
Toll-like receptor 8
Protein Classification
Membrane receptor
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Toll-like and Il-1 receptors
Uniprot ID
Q9NR97
Gene Name
TLR8
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000381 HEK-Blue hTLR8 Homo sapiens (Human)  1
1
IC50 = 22000 nM
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