Brief Information of the Compound and Protein
Compound Name
methyl 3-[[2-(4-hex-5-ynoxyphenyl)-4-oxochromen-3-yl]oxymethyl]benzoate
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Canonical SMILES
COC(=O)c1cccc(COc2c(oc3ccccc3c2=O)-c2ccc(OCCCCC#C)cc2)c1
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Compound Formula C30H26O6
Compound Structure
Protein Name
Broad substrate specificity ATP-binding cassette transporter ABCG2
Protein Classification
Transporter
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Primary active transporter
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ATP-binding cassette
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ABCG subfamily
Uniprot ID
Q9UNQ0
Gene Name
ABCG2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000462 HEKR2 Homo sapiens (Human)  1
1
EC50 = 43.8 nM
   TI
   LI
   LO
   TS
CL000415 MCF-7 MX100 Homo sapiens (Human)  1
1
EC50 = 33.7 nM
   TI
   LI
   LO
   TS