Brief Information of the Compound and Protein
Compound Name
N-[2-[2-[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]tetrazol-5-yl]-4,5-dimethoxyphenyl]-5-methoxy-4-oxochromene-2-carboxamide
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PubChem ID
CID: 11331551
SID: 16421562
Canonical SMILES
COc1cc2CCN(CCc3ccc(cc3)-n3nnc(n3)-c3cc(OC)c(OC)cc3NC(=O)c3cc(=O)c4c(OC)cccc4o3)Cc2cc1OC
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Compound Formula C39H38N6O8
Compound Structure
Protein Name
ATP-dependent translocase ABCB1
Protein Classification
Transporter
>
Primary active transporter
>
ATP-binding cassette
>
ABCB subfamily
Uniprot ID
P08183
Gene Name
ABCB1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000083 MCF-7 Homo sapiens (Human)  1
1
EC50 = 7.4 nM
   TI
   LI
   LO
   TS
CL000355 MES-SA/Dx5 Homo sapiens (Human)  1
1
EC50 = 5.9 nM
   TI
   LI
   LO
   TS