Brief Information of the Compound and Protein
Compound Name
7,8-difluoro-N-(1-propan-2-ylindazol-5-yl)quinazolin-4-amine
    Show/Hide
PubChem ID
CID: 154872583
Canonical SMILES
CC(C)n1ncc2cc(Nc3ncnc4c(F)c(F)ccc34)ccc12
    Show/Hide
Compound Formula C18H15F2N5
Compound Structure
Protein Name
Broad substrate specificity ATP-binding cassette transporter ABCG2
Protein Classification
Transporter
>
Primary active transporter
>
ATP-binding cassette
>
ABCG subfamily
Uniprot ID
Q9UNQ0
Gene Name
ABCG2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000839 MDCK2/BCRP Canis lupus familiaris (Dog)  1
1
IC50 = 1080 nM
   TI
   LI
   LO
   TS