Brief Information of the Compound and Protein
Compound Name
(3,4-dimethylthieno[2,3-b]pyridin-2-yl)-[4-(1H-indazole-3-carbonyl)piperazin-1-yl]methanone
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PubChem ID
CID: 154857461
Canonical SMILES
Cc1c(sc2nccc(C)c12)C(=O)N1CCN(CC1)C(=O)c1[nH]nc2ccccc12
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Compound Formula C22H21N5O2S
Compound Structure
Protein Name
Broad substrate specificity ATP-binding cassette transporter ABCG2
Protein Classification
Transporter
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Primary active transporter
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ATP-binding cassette
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ABCG subfamily
Uniprot ID
Q9UNQ0
Gene Name
ABCG2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000839 MDCK2/BCRP Canis lupus familiaris (Dog)  1
1
IC50 = 20300 nM
   TI
   LI
   LO
   TS