Brief Information of the Compound and Protein
Compound Name
3-chloro-N-(3-methylsulfanyl-1,2,4-thiadiazol-5-yl)thieno[2,3-b]pyridine-2-carboxamide
    Show/Hide
Canonical SMILES
CSc1nsc(NC(=O)c2sc3ncccc3c2Cl)n1
    Show/Hide
Compound Formula C11H7ClN4OS3
Compound Structure
Protein Name
Broad substrate specificity ATP-binding cassette transporter ABCG2
Protein Classification
Transporter
>
Primary active transporter
>
ATP-binding cassette
>
ABCG subfamily
Uniprot ID
Q9UNQ0
Gene Name
ABCG2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000839 MDCK2/BCRP Canis lupus familiaris (Dog)  1
1
IC50 = 1460 nM
   TI
   LI
   LO
   TS