Brief Information of the Compound and Protein
Compound Name
3-[(5-chloro-1,3-dimethylpyrazol-4-yl)methyl]-5-[3-methyl-6-(trifluoromethyl)thieno[2,3-b]pyridin-2-yl]-1,2,4-oxadiazole
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Canonical SMILES
Cc1nn(C)c(Cl)c1Cc1noc(n1)-c1sc2nc(ccc2c1C)C(F)(F)F
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Compound Formula C17H13ClF3N5OS
Compound Structure
Protein Name
Broad substrate specificity ATP-binding cassette transporter ABCG2
Protein Classification
Transporter
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Primary active transporter
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ATP-binding cassette
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ABCG subfamily
Uniprot ID
Q9UNQ0
Gene Name
ABCG2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000839 MDCK2/BCRP Canis lupus familiaris (Dog)  1
1
IC50 = 7330 nM
   TI
   LI
   LO
   TS