Brief Information of the Compound and Protein
Compound Name
4-[4-(2-methylquinolin-8-yl)sulfonylpiperazin-1-yl]thieno[3,2-c]pyridine
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PubChem ID
CID: 154860935
Canonical SMILES
Cc1ccc2cccc(c2n1)S(=O)(=O)N1CCN(CC1)c1nccc2sccc12
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Compound Formula C21H20N4O2S2
Compound Structure
Protein Name
Broad substrate specificity ATP-binding cassette transporter ABCG2
Protein Classification
Transporter
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Primary active transporter
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ATP-binding cassette
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ABCG subfamily
Uniprot ID
Q9UNQ0
Gene Name
ABCG2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000839 MDCK2/BCRP Canis lupus familiaris (Dog)  2
1
IC50 = 9070 nM
   TI
   LI
   LO
   TS
2
IC50 = 14200 nM
   TI
   LI
   LO
   TS