Brief Information of the Compound and Protein
Compound Name
N-(7,8-difluoroquinolin-3-yl)-4-propan-2-ylthiadiazole-5-carboxamide
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PubChem ID
CID: 154872584
Canonical SMILES
CC(C)c1nnsc1C(=O)Nc1cnc2c(F)c(F)ccc2c1
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Compound Formula C15H12F2N4OS
Compound Structure
Protein Name
Broad substrate specificity ATP-binding cassette transporter ABCG2
Protein Classification
Transporter
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Primary active transporter
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ATP-binding cassette
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ABCG subfamily
Uniprot ID
Q9UNQ0
Gene Name
ABCG2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000839 MDCK2/BCRP Canis lupus familiaris (Dog)  1
1
IC50 = 16200 nM
   TI
   LI
   LO
   TS