Brief Information of the Compound and Protein
Compound Name
5-[(2,5-dimethylquinolin-4-yl)oxymethyl]-3-(3,4,5-trimethoxyphenyl)-1,2,4-oxadiazole
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Canonical SMILES
COc1cc(cc(OC)c1OC)-c1noc(COc2cc(C)nc3cccc(C)c23)n1
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Compound Formula C23H23N3O5
Compound Structure
Protein Name
Broad substrate specificity ATP-binding cassette transporter ABCG2
Protein Classification
Transporter
>
Primary active transporter
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ATP-binding cassette
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ABCG subfamily
Uniprot ID
Q9UNQ0
Gene Name
ABCG2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000839 MDCK2/BCRP Canis lupus familiaris (Dog)  2
1
IC50 = 600 nM
   TI
   LI
   LO
   TS
2
IC50 = 1310 nM
   TI
   LI
   LO
   TS