Brief Information of the Compound and Protein
Compound Name
7,8-difluoro-N-(1-propan-2-ylindazol-5-yl)quinazolin-4-amine
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PubChem ID
CID: 154872583
Canonical SMILES
CC(C)n1ncc2cc(Nc3ncnc4c(F)c(F)ccc34)ccc12
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Compound Formula C18H15F2N5
Compound Structure
Protein Name
ATP-dependent translocase ABCB1
Protein Classification
Transporter
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Primary active transporter
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ATP-binding cassette
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ABCB subfamily
Uniprot ID
P08183
Gene Name
ABCB1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000135 A2780ADR Homo sapiens (Human)  1
1
IC50 = 13700 nM
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