Brief Information of the Compound and Protein
Compound Name
4-N-(2,4-dimethoxyphenyl)-6-N-[2-(5-propan-2-yl-1,3,4-thiadiazol-2-yl)ethyl]pyrimidine-4,6-diamine
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Canonical SMILES
COc1ccc(Nc2cc(NCCc3nnc(s3)C(C)C)ncn2)c(OC)c1
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Compound Formula C19H24N6O2S
Compound Structure
Protein Name
ATP-dependent translocase ABCB1
Protein Classification
Transporter
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Primary active transporter
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ATP-binding cassette
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ABCB subfamily
Uniprot ID
P08183
Gene Name
ABCB1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000135 A2780ADR Homo sapiens (Human)  1
1
IC50 = 16200 nM
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