Brief Information of the Compound and Protein
Compound Name
6-methoxy-4-[4-[(3-propan-2-yl-1,2,4-oxadiazol-5-yl)methyl]piperidin-1-yl]quinoline-3-carbonitrile
    Show/Hide
Canonical SMILES
COc1ccc2ncc(C#N)c(N3CCC(Cc4nc(no4)C(C)C)CC3)c2c1
    Show/Hide
Compound Formula C22H25N5O2
Compound Structure
Protein Name
ATP-dependent translocase ABCB1
Protein Classification
Transporter
>
Primary active transporter
>
ATP-binding cassette
>
ABCB subfamily
Uniprot ID
P08183
Gene Name
ABCB1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000135 A2780ADR Homo sapiens (Human)  2
1
IC50 = 2000 nM
   TI
   LI
   LO
   TS
2
IC50 = 5870 nM
   TI
   LI
   LO
   TS