Brief Information of the Compound and Protein
Compound Name
 Compound Info 
3-[(3-chloro-4-hydroxyphenyl)amino]-4-(2-nitrophenyl)-2,5-dihydro-1H-pyrrole-2,5-dione
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 PubChem ID
CID: 4210951
SID: 14828233
Canonical SMILES
Oc1ccc(NC2=C(C(=O)NC2=O)c2ccccc2N(=O)=O)cc1Cl
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Compound Formula C16H10ClN3O5
Compound Structure
Protein Name
 Protein Info 
Glycogen synthase kinase-3 beta
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
CMGC protein kinase group
>
CMGC protein kinase GSK family
Uniprot ID
P49841
Gene Name
GSK3B
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 54 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 34 nM
2 IC50 = 50 nM
3 IC50 = 77 nM
4 IC50 = 78 nM
5 IC50 = 90 nM
6 IC50 = 104 nM
7 IC50 = 380 nM
8 Ki = 24 nM