Brief Information of the Compound and Protein
Compound Name
 Compound Info 
5-[8-oxo-5-[4-(piperazin-1-ylmethyl)phenyl]-6-sulfanylidene-5,7-diazaspiro[3.4]octan-7-yl]-3-(trifluoromethyl)pyridine-2-carbonitrile
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 PubChem ID
CID: 130230029
Canonical SMILES
FC(F)(F)c1cc(cnc1C#N)N1C(=S)N(c2ccc(CN3CCNCC3)cc2)C2(CCC2)C1=O
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Compound Formula C24H23F3N6OS
Compound Structure
Protein Name
 Protein Info 
Androgen receptor
Protein Classification
Transcription factor
>
Nuclear receptor
>
Nuclear hormone receptor subfamily 3
>
Nuclear hormone receptor subfamily 3 group C
>
Nuclear hormone receptor subfamily 3 group C member 4
Uniprot ID
P10275
Gene Name
AR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000141 LNCaP
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 204 nM
   TI
   LI
   LO
   TS
2
IC50 = 355 nM
   TI
   LI
   LO
   TS