Brief Information of the Compound and Protein
Compound Name
9-hydroxy-5-[2-(3-methoxyphenyl)ethyl]indeno[1,2-b]indol-10-one
    Show/Hide
Canonical SMILES
COc1cccc(CCn2c3-c4ccccc4C(=O)c3c3c(O)cccc23)c1
    Show/Hide
Compound Formula C24H19NO3
Compound Structure
Protein Name
Broad substrate specificity ATP-binding cassette transporter ABCG2
Protein Classification
Transporter
>
Primary active transporter
>
ATP-binding cassette
>
ABCG subfamily
Uniprot ID
Q9UNQ0
Gene Name
ABCG2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  4
1
IC50 = 732 nM
   TI
   LI
   LO
   TS
2
Ki = 188 nM
   TI
   LI
   LO
   TS
3
Ki = 250 nM
   TI
   LI
   LO
   TS
4
Ki = 294 nM
   TI
   LI
   LO
   TS