Brief Information of the Compound and Protein
Compound Name
1-[N'-[3-(2-amino-4-methyl-1,3-thiazol-5-yl)propyl]carbamimidoyl]-3-[(1R)-1-phenylethyl]thiourea
    Show/Hide
Canonical SMILES
C[C@@H](NC(=S)\N=C(/N)NCCCc1sc(N)nc1C)c1ccccc1
    Show/Hide
Compound Formula C17H24N6S2
Compound Structure
Protein Name
Histamine H2 receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Histamine receptor
Uniprot ID
P25021
Gene Name
HRH2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000025 HEK-293T Homo sapiens (Human)  1
1
EC50 = 371.54 nM
   TI
   LI
   LO
   TS