Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(2S)-N-[(1S)-2-[[(2R)-3-(4-cyanophenyl)-1-(methylamino)-1-oxopropan-2-yl]amino]-2-oxo-1-phenylethyl]oxirane-2-carboxamide
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Canonical SMILES
CNC(=O)[C@@H](Cc1ccc(cc1)C#N)NC(=O)[C@@H](NC(=O)[C@@H]1CO1)c1ccccc1
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Compound Formula C22H22N4O4
Compound Structure
Protein Name
 Protein Info 
Tyrosine-protein kinase BTK
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Tec family
Uniprot ID
Q06187
Gene Name
BTK
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  3
1
IC50 = 84.2 nM
   TI
   LI
   LO
   TS
2
IC50 > 5920 nM
   TI
   LI
   LO
   TS
3
Ki = 1930 nM
   TI
   LI
   LO
   TS