Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(3R)-2-((3R)-4-(3-fluorophenyl)-3-(oxirane-2-carboxamido)butanoyl)-N-methyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxamide
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Canonical SMILES
CNC(=O)[C@H]1Cc2c([nH]c3ccccc23)CN1C(=O)C[C@@H](Cc1cccc(F)c1)NC(=O)C1CO1
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Compound Formula C26H27FN4O4
Compound Structure
Protein Name
 Protein Info 
Tyrosine-protein kinase BTK
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Tec family
Uniprot ID
Q06187
Gene Name
BTK
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  3
1
IC50 = 232 nM
   TI
   LI
   LO
   TS
2
IC50 > 5920 nM
   TI
   LI
   LO
   TS
3
Ki = 9270 nM
   TI
   LI
   LO
   TS