Brief Information of the Compound and Protein
Compound Name
6-((4-chloro-2-(trifluoromethyl)phenoxy)methyl)picolinic acid
    Show/Hide
PubChem ID
CID: 155154170
Canonical SMILES
O=C(O)c1cccc(COc2ccc(Cl)cc2C(F)(F)F)n1
    Show/Hide
Compound Formula C14H9ClF3NO3
Compound Structure
Protein Name
Mas-related G-protein coupled receptor member X4
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
Uniprot ID
Q96LA9
Gene Name
MRGPRX4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  6
1
IC50 = 5 nM
   TI
   LI
   LO
   TS
2
IC50 = 7 nM
   TI
   LI
   LO
   TS
3
IC50 = 9 nM
   TI
   LI
   LO
   TS
4
IC50 = 10 nM
   TI
   LI
   LO
   TS
5
IC50 = 11 nM
   TI
   LI
   LO
   TS
6
IC50 < 100 nM
   TI
   LI
   LO
   TS