Brief Information of the Compound and Protein
Compound Name
3-methyl-5-((2-methyl-4-(trifluoromethyl)phenoxy)methyl)benzoic acid
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PubChem ID
CID: 155154251
Canonical SMILES
Cc1cc(COc2ccc(C(F)(F)F)cc2C)cc(C(=O)O)c1
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Compound Formula C17H15F3O3
Compound Structure
Protein Name
Mas-related G-protein coupled receptor member X4
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
Uniprot ID
Q96LA9
Gene Name
MRGPRX4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  6
1
IC50 = 24 nM
   TI
   LI
   LO
   TS
2
IC50 = 25 nM
   TI
   LI
   LO
   TS
3
IC50 = 35 nM
   TI
   LI
   LO
   TS
4
IC50 = 41 nM
   TI
   LI
   LO
   TS
5
IC50 = 63 nM
   TI
   LI
   LO
   TS
6
IC50 < 100 nM
   TI
   LI
   LO
   TS