Brief Information of the Compound and Protein
Compound Name
(1-butyl-7-fluoroindol-3-yl)-(6-fluoro-1-methylbenzimidazol-2-yl)methanone
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Canonical SMILES
CCCCn1cc(C(=O)c2nc3ccc(F)cc3n2C)c2cccc(F)c12
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Compound Formula C21H19F2N3O
Compound Structure
Protein Name
Proprotein convertase subtilisin/kexin type 9
Protein Classification
Enzyme
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Protease
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Serine protease
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Serine protease SB clan
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Serine protease S8A subfamily
Uniprot ID
Q8NBP7
Gene Name
PCSK9
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000063 Hep-G2 Homo sapiens (Human)  1
1
EC50 = 0.28 nM
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