Brief Information of the Compound and Protein
Compound Name
(6-fluoro-1-methylbenzimidazol-2-yl)-[7-fluoro-1-(4-morpholin-4-ylbutyl)indol-3-yl]methanone
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Canonical SMILES
Cn1c(nc2ccc(F)cc12)C(=O)c1cn(CCCCN2CCOCC2)c2c(F)cccc12
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Compound Formula C25H26F2N4O2
Compound Structure
Protein Name
Proprotein convertase subtilisin/kexin type 9
Protein Classification
Enzyme
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Protease
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Serine protease
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Serine protease SB clan
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Serine protease S8A subfamily
Uniprot ID
Q8NBP7
Gene Name
PCSK9
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000063 Hep-G2 Homo sapiens (Human)  1
1
EC50 = 88 nM
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