Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-[4-[(S)-[2-(4-cyanoanilino)pyrimidin-4-yl]-hydroxymethyl]-3,5-difluorophenyl]benzonitrile
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Canonical SMILES
O[C@H](c1ccnc(Nc2ccc(cc2)C#N)n1)c1c(F)cc(cc1F)-c1ccc(cc1)C#N
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Compound Formula C25H15F2N5O
Compound Structure
Protein Name
 Protein Info 
Reverse transcriptase
Protein Classification
Enzyme
Uniprot ID
Q9WKE8
Gene Name
REVERSE TRANSCRIPTASE
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000247 MT-4
 Cell Line Info 
Homo sapiens (Human)  5
1
EC50 = 8.4 nM
   TI
   LI
   LO
   TS
2
EC50 = 36.4 nM
   TI
   LI
   LO
   TS
3
EC50 = 88.7 nM
   TI
   LI
   LO
   TS
4
EC50 = 341.4 nM
   TI
   LI
   LO
   TS
5
EC50 = 2252.9 nM
   TI
   LI
   LO
   TS