Brief Information of the Compound and Protein
| Compound Name |
2-[[2-ethyl-6-[4-[2-(3-hydroxyazetidin-1-yl)-2-oxoethyl]piperazin-1-yl]-8-methylimidazo[1,2-a]pyridin-3-yl]-methylamino]-4-(4-fluorophenyl)-1,3-thiazole-5-carbonitrile
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PubChem ID | |||||
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Compound Structure |
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| Protein Name |
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2
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Protein Classification |
Enzyme
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| Uniprot ID | Gene Name | ENPP2 |
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Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
| Cell Line ID | Cell Line Name | Cell Line Organism | |
| CL000013 | Sf9 | Spodoptera frugiperda (Fall armyworm) | 1 |
| 1 |
IC50 = 3.7 nM
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TI
LI
LO
TS
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Biochemical Assays
| 1 | IC50 = 0.01 nM | ||
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| 2 | IC50 = 1.3 nM | ||
| 3 | IC50 = 2.9 nM | ||
| 4 | IC50 = 3.1 nM | ||
| 5 | IC50 = 3.9 nM | ||
| 6 | IC50 = 100 nM | ||
| 7 | IC50 = 131 nM | ||
| 8 | IC50 = 242 nM | ||
| 9 | IC50 > 100 nM | ||
| 10 | Ki = 15 nM | ||